| Date | Location | Result | |
| 02/28/22 | Indianapolis, IN | UIndy 87, Missouri S&T 60 | Box score |
| 02/26/22 | Rolla, MO | Missouri S&T 80, Lewis 61 | Box score |
| 02/24/22 | Rolla, MO | Ill. Springfield 76, Missouri S&T 58 | Box score |
| 02/19/22 | Evansville, IN | Southern Ind. 72, Missouri S&T 65 | Box score |
| 02/17/22 | Indianapolis, IN | UIndy 80, Missouri S&T 50 | Box score |
| 02/14/22 | Saint Charles, MO | Lindenwood (MO) 101, Missouri S&T 66 | Box score |
| 02/12/22 | Rolla, MO | Mo.-St. Louis 75, Missouri S&T 59 | Box score |
| 02/10/22 | Rolla, MO | Missouri S&T 75, McKendree 70 (OT) | Box score |
| 02/05/22 | St. Louis, MO | Maryville (MO) 73, Missouri S&T 72 | Box score |
| 01/29/22 | Springfield, MO | Drury 82, Missouri S&T 76 | Box score |
| 01/22/22 | Rolla, MO | Missouri S&T 62, Rockhurst 43 | Box score |
| 01/20/22 | Rolla, MO | Missouri S&T 75, Southwest Baptist 71 | Box score |
| 01/17/22 | Quincy, IL | Missouri S&T 90, Quincy 84 (OT) | Box score |
| 01/15/22 | Rolla, MO | William Jewell 75, Missouri S&T 65 | Box score |
| 01/13/22 | Rolla, MO | Truman 81, Missouri S&T 72 | Box score |
| 01/08/22 | St. Louis, MO | Mo.-St. Louis 83, Missouri S&T 72 | Box score |
| 01/06/22 | Rolla, MO | UIndy 78, Missouri S&T 61 | Box score |
| 01/02/22 | Kansas City, MO | Missouri S&T 82, Rockhurst 62 | Box score |
| 12/20/21 | Rolla, MO | Missouri S&T 76, Culver-Stockton 66 | Box score |
| 12/11/21 | Rolla, MO | Missouri S&T 94, Westminster (MO) 57 | Box score |
| 12/08/21 | Rolla, MO | Missouri S&T 95, Webster 56 | Box score |
| 12/04/21 | Bolivar, MO | Southwest Baptist 70, Missouri S&T 51 | Box score |
| 12/02/21 | Liberty, MO | William Jewell 81, Missouri S&T 77 | Box score |
| 11/29/21 | Rolla, MO | Missouri S&T 80, Drury 76 | Box score |
| 11/27/21 | Rolla, MO | Missouri S&T 91, Principia 60 | Box score |
| 11/24/21 | Springfield, MO | Southeastern Okla. 104, Missouri S&T 102 | Box score |
| 11/23/21 | Springfield, MO | Ark.-Monticello 64, Missouri S&T 63 | Box score |
| 11/12/21 | Rolla, MO | Trevecca Nazarene 79, Missouri S&T 72 | Box score |